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PDGFRB-associated chronic eosinophilic leukemia

अंतिम अद्यतन 2 Oct 2024

मरीज की संपादकीय दिशानिर्देशों

PDGFRB-associated chronic eosinophilic leukemia is a type of cancer of blood-forming cells. It is characterised by an elevated number of white blood cells called eosinophils in the blood. These cells help fight infections by certain parasites and are involved in the inflammation associated with allergic reactions. However, these circumstances do not account for the increased number of eosinophils in PDGFRB-associated chronic eosinophilic leukemia. Some people with this condition have an increased number of other types of white blood cells, such as neutrophils or mast cells, in addition to eosinophils. People with this condition can have an enlarged spleen (splenomegaly) or enlarged liver (hepatomegaly). Some affected individuals develop skin rashes, likely as a result of an abnormal immune response due to the increased number of eosinophils.

विवरण

PDGFRB-associated chronic eosinophilic leukemia is a type of cancer of blood-forming cells. It is characterised by an elevated number of white blood cells called eosinophils in the blood. These cells help fight infections by certain parasites and are involved in the inflammation associated with allergic reactions. However, these circumstances do not account for the increased number of eosinophils in PDGFRB-associated chronic eosinophilic leukemia. Some people with this condition have an increased number of other types of white blood cells, such as neutrophils or mast cells, in addition to eosinophils. People with this condition can have an enlarged spleen (splenomegaly) or enlarged liver (hepatomegaly). Some affected individuals develop skin rashes, likely as a result of an abnormal immune response due to the increased number of eosinophils.

Inheritance patterns

The source lists the following possible inheritance patterns: Pattern unknown. More than one pattern can apply in different cases.

Related genes

Other names

Chronic myelomonocytic leukemia with eosinophilia associated with t(5;12)

Myeloid neoplasms associated with PDGFRB rearrangement

Myeloid neoplasms with PDGFRB rearrangement

Myeloid/lymphoid neoplasms with PDGFRB rearrangement

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  • 2 Oct 2024 | नवीनतम संस्करण
  • 1 Feb 2013 | मूल रूप से प्रकाशित

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