Can I take Calcium and Ciprofloxacin together?

Why this happens

Calcium binds to the ciprofloxacin in your stomach or gut, forming a 'complex' that is too large for your body to absorb. Instead of entering your blood, the medicine simply passes through your system.

What you should do

Do not take calcium supplements, antacids containing calcium, or large amounts of dairy products at the same time as ciprofloxacin. You should take ciprofloxacin at least 2 hours before or 6 hours after taking any calcium-containing products.

Important precautions

Drug interaction (spacing)

Do not take calcium supplements at the same time as ciprofloxacin. Calcium can stop ciprofloxacin from being absorbed properly. Take ciprofloxacin at least 2 hours before or 6 hours after any calcium-containing products.

Tendon damage

Stop taking ciprofloxacin and seek immediate medical help if you experience any pain, swelling, or inflammation in your tendons (such as the ankle or calf), as this medicine increases the risk of tendon rupture.

Sun sensitivity

Ciprofloxacin makes your skin much more sensitive to sunlight. Avoid bright sunlight and do not use sunbeds, as you may burn very severely.

Food and drink warnings

Dairy products (milk, cheese, yoghurt) and calcium-fortified juices

Do not take ciprofloxacin at the same time as dairy products or calcium-fortified drinks. These can significantly reduce the amount of medicine absorbed by your body, making it less effective. You should take ciprofloxacin at least 2 hours before or 6 hours after consuming these items. (Note: It is fine to eat these as part of a main meal, but avoid them as a standalone snack or drink when taking your dose).

Caffeine (coffee, tea, cola, energy drinks)

Ciprofloxacin can stop your body from breaking down caffeine. This can lead to a build-up of caffeine in your system, making you feel shaky, anxious, or causing a racing heart and insomnia. It is best to limit your caffeine intake while taking this antibiotic.

Multivitamins and minerals (Iron, Magnesium, Zinc, Aluminium)

Supplements or fortified foods containing these minerals can stop these antibiotics from working. Take your medicine at least 2 hours before or 4-6 hours after any supplements or antacids.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.