मुख्य सामग्री पर जाएं

dual specificity tyrosine phosphorylation regulated kinase 1A

यह DYRK1A gene provides instructions for making an enzyme that is important in the development of the nervous system. The DYRK1A enzyme is a kinase, which means that it adds a cluster of oxygen and phosphorus atoms (a phosphate group) to other proteins through a process called phosphorylation. Phosphorylation of proteins helps to control (regulate) their activity.

Normal function

यह DYRK1A gene provides instructions for making an enzyme that is important in the development of the nervous system. The DYRK1A enzyme is a kinase, which means that it adds a cluster of oxygen and phosphorus atoms (a phosphate group) to other proteins through a process called phosphorylation. Phosphorylation of proteins helps to control (regulate) their activity.

The proteins whose activity the DYRK1A enzyme helps regulate are involved in various processes in cells, including cell growth and division (proliferation) and the process by which cells mature to carry out specific functions (differentiation). In nerve cells (neurons), the DYRK1A enzyme is involved in the formation and maturation of dendritic spines from dendrites. Dendrites are specialized extensions from neurons that are essential for the transmission of nerve impulses. Dendritic spines are small outgrowths from dendrites that further help transmit nerve impulses and increase communication between neurons.

Conditions referring to this gene or chromosome

Other names

dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

dual specificity YAK1-related kinase

DYRK

DYRK1

HP86

MNB

mnb protein kinase homolog hp86

MNB/DYRK protein kinase

MNBH

MRD7

protein kinase minibrain homolog

serine/threonine kinase MNB

serine/threonine-specific protein kinase

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