purine rich element binding protein A
अंतिम अद्यतन 18 Aug 2020
मरीज की संपादकीय दिशानिर्देशों
- डाउनलोडडाउनलोड
- साझा करें
- Language
- चर्चा
- ऑडियो संस्करण
- Google पर पसंदीदा स्रोतों में जोड़ें
यह PURA gene provides instructions for making a protein called Pur-alpha (Purα), which is able to attach (bind) to DNA and RNA (a molecular cousin of DNA). This protein has multiple roles in cells, including controlling the activity of genes (gene transcription) and aiding in the copying (replication) of DNA.
Normal function
यह PURA gene provides instructions for making a protein called Pur-alpha (Purα), which is able to attach (bind) to DNA and RNA (a molecular cousin of DNA). This protein has multiple roles in cells, including controlling the activity of genes (gene transcription) and aiding in the copying (replication) of DNA.
The Purα protein is important for normal brain development. The protein helps direct the growth and division of nerve cells (neurons). It may also be involved in the formation or maturation of myelin, the protective substance that covers nerves and promotes the efficient transmission of nerve impulses.
Conditions referring to this gene or chromosome
Other names
MRD31
PUR-ALPHA
PUR1
PURALPHA
purine-rich single-stranded DNA-binding protein alpha
transcriptional activator protein Pur-alpha
Related patient information and medicines
Patient information leaflet
क्या मैं एलोप्यूरिनॉल और नॉर्ट्रिप्टिलीन को एक साथ ले सकता हूँ?
Water / Fluids It is important to drink plenty of fluids (at least 2 to... This helps to prevent the formation of kidney stones and ensures the medicine works correctly to flush uric acid from your system. Purine-rich foods (e.g., red meat, seafood) While not a direct drug interaction, allopurinol is used to treat gout. Eating foods high in.
Patient information leaflet
क्या मैं एलोप्यूरिनॉल और मिर्टाज़ापाइन को एक साथ ले सकता हूँ?
Water / Fluids It is important to drink plenty of fluids (at least 2 to... This helps to prevent the formation of kidney stones and ensures the medicine works correctly to flush uric acid from your system. Purine-rich foods (e.g., red meat, seafood) While not a direct drug interaction, allopurinol is used to treat gout. Eating foods high in.
Patient information leaflet
क्या मैं एलोप्यूरिनॉल और रोसुवास्टेटिन को एक साथ ले सकता हूँ?
Water / Fluids It is important to drink plenty of fluids (at least 2 to... This helps to prevent the formation of kidney stones and ensures the medicine works correctly to flush uric acid from your system. Purine-rich foods (e.g., red meat, seafood) While not a direct drug interaction, allopurinol is used to treat gout. Eating foods high in.
Patient information leaflet
क्या मैं बायोटिन और विटामिन डी को एक साथ ले सकता हूँ?
Raw egg whites Consuming large amounts of raw egg whites over a long period can prevent your body from absorbing biotin. This is because raw egg whites contain a protein called avidin that binds to biotin. Cooked eggs do not cause this issue. Using other medicines T... Our Medicines Interaction Checker helps you check whether your prescriptions,.
Patient information leaflet
क्या मैं लायन मेन और माचा को एक साथ ले सकता हूँ?
Caffeine Matcha is very high in caffeine. You should be cautious about consuming other caffeinated drinks (like coffee or energy drinks) alongside it, as this can lead to jitteriness, increased heart rate, and difficulty sleeping. Iron-rich foods The tannins in matcha can bind to iron from plant-based foods (non-heme iron), making it harder for.
Patient information leaflet
डुकन आहार
The Dukan diet is a weight loss plan devised by French doctor, Pierre Dukan. What is the Dukan diet. The Dukan diet was. It is one of the high-protein diets in which both fats and carbohydrates are restricted. This is unlike the Atkins diet , ketogenic diet, and other low-carbohydrate:high-fat (LCHF) diets, in which fat is not restricted. The.
अधिक पठन और संदर्भ
- purine rich element binding protein A; MedlinePlus, National Library of Medicine.
- Brown N, Burgess T, Forbes R, McGillivray G, Kornberg A, Mandelstam S, Stark Z. 5q31.3 Microdeletion syndrome: clinical and molecular characterization of two further cases. Am J Med Genet A. 2013 Oct;161A(10):2604-8. doi: 10.1002/ajmg.a.36108. Epub 2013 Aug 15.
- Hokkanen S, Feldmann HM, Ding H, Jung CK, Bojarski L, Renner-Muller I, Schuller U, Kretzschmar H, Wolf E, Herms J. Lack of Pur-alpha alters postnatal brain development and causes megalencephaly. Hum Mol Genet. 2012 Feb 1;21(3):473-84. doi: 10.1093/hmg/ddr476. Epub 2011 Oct 18.
- Hosoki K, Ohta T, Natsume J, Imai S, Okumura A, Matsui T, Harada N, Bacino CA, Scaglia F, Jones JY, Niikawa N, Saitoh S. Clinical phenotype and candidate genes for the 5q31.3 microdeletion syndrome. Am J Med Genet A. 2012 Aug;158A(8):1891-6. doi: 10.1002/ajmg.a.35439. Epub 2012 Jun 18.
- Lalani SR, Zhang J, Schaaf CP, Brown CW, Magoulas P, Tsai AC, El-Gharbawy A, Wierenga KJ, Bartholomew D, Fong CT, Barbaro-Dieber T, Kukolich MK, Burrage LC, Austin E, Keller K, Pastore M, Fernandez F, Lotze T, Wilfong A, Purcarin G, Zhu W, Craigen WJ, McGuire M, Jain M, Cooney E, Azamian M, Bainbridge MN, Muzny DM, Boerwinkle E, Person RE, Niu Z, Eng CM, Lupski JR, Gibbs RA, Beaudet AL, Yang Y, Wang MC, Xia F. Mutations in PURA cause profound neonatal hypotonia, seizures, and encephalopathy in 5q31.3 microdeletion syndrome. Am J Hum Genet. 2014 Nov 6;95(5):579-83. doi: 10.1016/j.ajhg.2014.09.014. Epub 2014 Oct 16.
- Shimojima K, Isidor B, Le Caignec C, Kondo A, Sakata S, Ohno K, Yamamoto T. A new microdeletion syndrome of 5q31.3 characterized by severe developmental delays, distinctive facial features, and delayed myelination. Am J Med Genet A. 2011 Apr;155A(4):732-6. doi: 10.1002/ajmg.a.33891. Epub 2011 Mar 15.
- Tanaka AJ, Bai R, Cho MT, Anyane-Yeboa K, Ahimaz P, Wilson AL, Kendall F, Hay B, Moss T, Nardini M, Bauer M, Retterer K, Juusola J, Chung WK. De novo mutations in PURA are associated with hypotonia and developmental delay. Cold Spring Harb Mol Case Stud. 2015 Oct;1(1):a000356. doi: 10.1101/mcs.a000356.
- Weber J, Bao H, Hartlmuller C, Wang Z, Windhager A, Janowski R, Madl T, Jin P, Niessing D. Structural basis of nucleic-acid recognition and double-strand unwinding by the essential neuronal protein Pur-alpha. Elife. 2016 Jan 8;5:e11297. doi: 10.7554/eLife.11297.
- White MK, Johnson EM, Khalili K. Multiple roles for Puralpha in cellular and viral regulation. Cell Cycle. 2009 Feb 1;8(3):1-7. doi: 10.4161/cc.8.3.7585. Epub 2009 Feb 10.
बातचीत में शामिल हों
हमारे में दूसरों के साथ अपने विचार या अनुभव साझा करें रोगी समुदायों.
पूछें, साझा करें, जुड़ें।.
चर्चाओं को ब्राउज़ करें, प्रश्न पूछें, और सैकड़ों स्वास्थ्य विषयों पर अनुभव साझा करें।.
पेशेंट न्यूज़लेटर के लिए साइन अप करें
आपकी साप्ताहिक खुराक स्पष्ट, विश्वसनीय स्वास्थ्य सलाह की - जो आपको सूचित, आत्मविश्वासी और नियंत्रण में महसूस करने में मदद करने के लिए लिखी गई है।.
सदस्यता लेने पर आप हमारी स्वीकार करते हैं गोपनीयता नीति. आप किसी भी समय सदस्यता समाप्त कर सकते हैं। हम कभी भी आपका डेटा नहीं बेचते।.