Can I take 500 and Apixaban together?

Why this happens

Both medicines affect how your blood clots, but in different ways. Apixaban is an anticoagulant (blood thinner) that slows down the clotting process. Naproxen is an NSAID that makes platelets (cells that help blood clot) less sticky and can also irritate the lining of the stomach. When used together, their effects add up, making it much harder for your body to stop any bleeding.

Do not take naproxen while you are on apixaban unless specifically instructed and monitored by your doctor. If you need pain relief, paracetamol is usually a safer choice, but you should always check with your pharmacist first. Seek immediate medical help if you notice signs of bleeding, such as dark 'coffee ground' vomit, black tarry stools, unexplained bruising, or a nosebleed that will not stop.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.