Can I take Aspirin and Lansoprazole together?

Why this happens

Aspirin inhibits prostaglandins that protect the stomach lining, while lansoprazole reduces the production of gastric acid, thereby providing a protective effect against aspirin-induced gastric mucosal damage.

What you should do

It is safe and often recommended to take these together, especially if you are at risk of stomach issues. Take the lansoprazole at least 30 to 60 minutes before food (usually in the morning) for it to work best. If you notice any unusual stomach pain or black, tarry stools, contact your doctor.

Important precautions

Asthma

Do not take aspirin if you have a history of asthma triggered by aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs), as it can cause a severe, life-threatening asthma attack.

Pregnancy (third trimester)

Do not take aspirin during the last 3 months of pregnancy (third trimester) as it can cause serious heart and kidney problems in the unborn baby and increase the risk of bleeding during delivery.

Children under 16 years old

Never give aspirin to children or teenagers under 16 unless specifically prescribed by a doctor. It is linked to Reye’s syndrome, a very rare but life-threatening condition affecting the brain and liver.

Food and drink warnings

Alcohol

Drinking alcohol while taking aspirin can increase the risk of irritation and bleeding in your stomach. It is best to limit alcohol intake or avoid it altogether if you have a history of stomach issues.

Food (Timing)

Lansoprazole works best when taken at least 30 minutes before a meal. Taking it with or after food can slow down how quickly the medicine is absorbed into your system, making it less effective.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.