मुख्य सामग्री पर जाएं

डिसल्फिराम टैबलेट्स

Antabuse

Disulfiram is a treatment option for alcohol dependency. It acts as a deterrent.

You must not drink ANY alcohol with disulfiram. It will make you feel very unwell and is potentially dangerous.

Keep your appointments with your doctor and counsellor so that your progress can be monitored.

एक नजर में

  • Disulfiram is a medicine used to support treatment for alcohol dependency.

  • It works by causing very unpleasant reactions if you drink even a small amount of alcohol.

  • You must not drink alcohol for at least 24 hours before starting disulfiram.

  • Avoid all products containing alcohol, including some toiletries and liquid medicines.

  • Common side-effects include feeling sick, tiredness, and tingling in hands.

About disulfiram

दवा का प्रकार

Aldehyde dehydrogenase inhibitor

के लिए उपयोग किया जाता है

Support treatment for alcohol dependency

जिसे कहा जाता है

Antabuse®

के रूप में उपलब्ध

Tablets

Disulfiram is used alongside other treatments and counselling for alcohol dependency. It is only suitable for people who have been through detoxification ('detox') and have stopped drinking alcohol. It acts as a deterrent to drinking further alcohol.

Disulfiram works by interfering with the way your body breaks down alcohol. Usually when you drink alcohol, your body breaks the alcohol down into a substance called acetaldehyde. This is then broken down further so that it can be removed from your body. Disulfiram blocks the enzyme which breaks down the acetaldehyde. This leads to high levels of acetaldehyde in your blood and causes an unpleasant effect.

If you drink even a small amount of alcohol with disulfiram, it will produce an extremely unpleasant reaction. It will give you a throbbing headache, a flushed face, and the sensation of having a 'thumping heart' (palpitations), and it will make you feel very sick. This reaction starts within about 10 minutes of drinking alcohol and can last for several hours. Knowing this will happen will help stop you from drinking alcohol. Because drinking larger amounts of alcohol can cause potentially dangerous reactions, disulfiram is only prescribed by specialists to people who are determined to stay off alcohol.

Before taking disulfiram

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking disulfiram it is important that your doctor knows:

  • If you are pregnant, trying for a baby or breastfeeding.

  • If you have a problem with your heart, or if you have high blood pressure.

  • If you have had a mental health problem called psychosis, or if you have ever had a personality disorder.

  • If you have had a stroke or a transient ischaemic attack (TIA).

  • If you have any problems with the way your liver works, or the way your kidneys work.

  • If you have diabetes.

  • यदि आपको मिर्गी है।.

  • If you have problems with your breathing.

  • If you have a rare inherited condition called porphyria.

  • यदि आप कोई अन्य दवाएं ले रहे हैं। इसमें वे सभी दवाएं शामिल हैं जो आप बिना पर्ची के खरीद सकते हैं, साथ ही हर्बल और पूरक दवाएं भी शामिल हैं।.

  • यदि आपको कभी किसी दवा से एलर्जी की प्रतिक्रिया हुई है।.

How to take disulfiram

  • Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The manufacturer's leaflet will give you more information about disulfiram and a full list of the side-effects which you may experience from taking it.

  • It is important that you have not drunk any alcohol for at least 24 hours before you take your first dose of disulfiram.

  • Take disulfiram exactly as your doctor tells you to. You may be asked to take several tablets a day during the first few days of treatment, but after this your dose will be reduced. As a guide, the usual recommended daily dose is one 200 mg tablet, although your dose may be different to this.

  • If you forget to take a dose, take it as soon as you remember, if it is still within 12 hours of when the dose was due. If you do not remember until more than 12 hours later, skip the missed dose. Do not take two doses together to make up for a forgotten dose.

अपने उपचार से अधिकतम लाभ प्राप्त करना

  • Disulfiram will be started in hospital or in a clinic, and then it is supervised by a specialist. Keep your regular appointments with your doctor and counsellor. This is so your progress can be checked on a regular basis.

  • Make sure your family and friends know how important it is that you do not drink any alcohol, so that they can be a support to you. Even low alcohol, 'non-alcohol' or 'alcohol-free' beers and wines may cause a reaction.

  • Even relatively small amounts of alcohol with disulfiram can produce severe reactions. Many liquid medicines, toiletries and mouthwashes contain sufficient alcohol to produce an effect. Always read the contents on the label and avoid any product which contains alcohol. If you buy any medicines, check with a pharmacist that they are safe for you to take.

Can disulfiram cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with disulfiram. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Disulfiram side-effects

अगर मुझे यह अनुभव होता है तो मैं क्या कर सकता हूँ?

Feeling sick (nausea) or being sick (vomiting)

सरल भोजन पर टिके रहें - समृद्ध या मसालेदार खाद्य पदार्थों से बचें

Feeling tired or sleepy (especially at the start)

Do not drive and do not use tools or machines until you feel better

Tingling feelings in your hands, bad breath, itchy red skin reactions, reduced interest in sex, mood changes

If any of these become troublesome, speak with your doctor

If you experience any other symptoms which you think may be due to this medicine, discuss them with your doctor or pharmacist.

How to store disulfiram

  • सभी दवाओं को बच्चों की पहुँच और दृष्टि से दूर रखें।.

  • ठंडी, सूखी जगह पर रखें, सीधे गर्मी और रोशनी से दूर।.

सभी दवाओं के बारे में महत्वपूर्ण जानकारी

सभी दवाओं के बारे में महत्वपूर्ण जानकारी

निर्धारित खुराक से अधिक कभी न लें। यदि आपको संदेह है कि आपने या किसी और ने इस दवा की अधिक मात्रा ले ली है, तो अपने स्थानीय अस्पताल के दुर्घटना और आपातकालीन विभाग में जाएं। कंटेनर को अपने साथ ले जाएं, भले ही वह खाली हो।.

यह दवा आपके लिए है। इसे कभी भी अन्य लोगों को न दें, भले ही उनकी स्थिति आपकी जैसी ही क्यों न लगे।.

If you are having an operation or any dental treatment, tell the person carrying out the treatment which medicines you are taking.

पुरानी या अनचाही दवाइयाँ न रखें। उन्हें अपने स्थानीय फार्मेसी में ले जाएँ, जो उन्हें आपके लिए नष्ट कर देगा।.

यदि इस दवा के बारे में आपके कोई प्रश्न हैं तो अपने फार्मासिस्ट से पूछें।.

दवा या टीके के दुष्प्रभावों की रिपोर्ट करें

यदि आपको दुष्प्रभाव महसूस होते हैं, तो आप उन्हें ऑनलाइन रिपोर्ट कर सकते हैं येलो कार्ड वेबसाइट.

लक्षण जाँचकर्ता

दवाओं को मिलाने के बारे में अनिश्चित?

दवाओं, सप्लीमेंट्स और खाद्य पदार्थों के बीच संभावित इंटरैक्शन की जांच करें, उन्हें एक साथ लेने से पहले।.

अक्सर पूछे जाने वाले प्रश्न

What is the purpose of taking disulfiram to help with alcohol dependency?

Disulfiram acts as a deterrent to drinking alcohol. It works by interfering with how your body processes alcohol, leading to unpleasant physical reactions if you consume even a small amount of alcohol while taking the medication.

How soon will I experience a reaction if I drink alcohol while on disulfiram, and how long does it last?

If you drink alcohol with disulfiram, you will typically experience a reaction within about 10 minutes. This unpleasant reaction, including headache, flushed face, palpitations, and severe sickness, can last for several hours.

Are there any products I should avoid besides alcoholic drinks while taking disulfiram?

Yes, you should avoid any products containing alcohol. This includes many liquid medicines, toiletries, and mouthwashes. Always read product labels carefully and check with a pharmacist if you are unsure about any over-the-counter medicine.

What should I do if I forget to take a dose of disulfiram?

If you forget a dose, take it as soon as you remember, but only if it's within 12 hours of when you were supposed to take it. If more than 12 hours have passed, skip the missed dose and do not take two doses together to catch up.

What should I do if I experience side-effects that become bothersome?

While some side-effects like feeling sick or tired often improve as your body adjusts, you should speak with your doctor or pharmacist if any side-effects, such as tingling in your hands, bad breath, itchy skin, reduced interest in sex, or mood changes, continue or become troublesome.

Who supervises my treatment with disulfiram after I start taking it?

Disulfiram treatment is typically started in a hospital or clinic and then supervised by a specialist. It's important to keep your regular appointments with your doctor and counsellor so your progress can be monitored.

अधिक पठन और संदर्भ

लेखक के बारे मेंपूरा जीवन परिचय देखें

लेखक की छवि

Michael Stewart, MRPharmS

दवा पत्रक समीक्षा प्रबंधक – ठेकेदार, फार्मासिस्ट

BPharm (Hons), MRPharmS

माइकल मिडलैंड्स और साउथ यॉर्कशायर में एक सामुदायिक फार्मासिस्ट हैं, जो दवाओं और चिकित्सा स्थितियों पर सलाह देने में 20 से अधिक वर्षों का अनुभव रखते हैं। उनके पास स्वास्थ्य देखभाल प्रशिक्षण में मजबूत पृष्ठभूमि है, उन्होंने फार्मेसी टीमों और आवासीय देखभाल सेटिंग्स के कर्मचारियों, जिनमें नर्सें शामिल हैं, के लिए प्रशिक्षण पाठ्यक्रम तैयार और प्रस्तुत किए हैं। उन्होंने समुदाय में कम तीव्रता वाली स्थितियों के प्रबंधन के लिए फार्मेसी सलाहकार बोर्डों में भी योगदान दिया है।.

समीक्षक के बारे में

लेखक की छवि

Sid Dajani

सुल्तान दाजानी ने 1994 में लंदन स्कूल ऑफ फार्मेसी से योग्यता प्राप्त की और 1842 में इसकी स्थापना के बाद से रॉयल फार्मास्यूटिकल सोसाइटी परिषद के सबसे युवा निर्वाचित सदस्य बने।.

लेख का इतिहास

इस पृष्ठ पर दी गई जानकारी योग्य चिकित्सकों द्वारा लिखी और सहकर्मी समीक्षा की गई है।.

  • Next review due: 28 Nov 2027
  • 29 May 2023 | नवीनतम संस्करण

    द्वारा अंतिम अपडेट

    Michael Stewart, MRPharmS

    द्वारा सहकर्मी समीक्षा की गई

    Sid Dajani
फ्लू पात्रता जाँचकर्ता

पूछें, साझा करें, जुड़ें।.

चर्चाओं को ब्राउज़ करें, प्रश्न पूछें, और सैकड़ों स्वास्थ्य विषयों पर अनुभव साझा करें।.

पेशेंट न्यूज़लेटर के लिए साइन अप करें

आपकी साप्ताहिक खुराक स्पष्ट, विश्वसनीय स्वास्थ्य सलाह की - जो आपको सूचित, आत्मविश्वासी और नियंत्रण में महसूस करने में मदद करने के लिए लिखी गई है।.

कृपया एक मान्य ईमेल पता दर्ज करें

सदस्यता लेने पर आप हमारी स्वीकार करते हैं गोपनीयता नीति. आप किसी भी समय सदस्यता समाप्त कर सकते हैं। हम कभी भी आपका डेटा नहीं बेचते।.