Lofexidine tablets
BritLofex, Lucemyra
द्वारा सहकर्मी समीक्षा की गई Sid Dajaniद्वारा अंतिम अपडेट Michael Stewart, MRPharmSअंतिम अद्यतन 11 Feb 2025
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क्लिनिकल लेखक का नोट Michael Stewart 01/03/2022: BritLofex® tablets were discontinued in the UK in October 2018. At the time of review there are no branded or generic products containing lofexidine available in the UK. Lofexidine may still be available in other countries. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.
It is usual to take four tablets over the first day. Your dose will then be increased over the next few days to suit your needs. A course of treatment usually lasts 7-10 days.
The main side-effects are dizziness, dry mouth and feeling sleepy.
At the end of your treatment your dose will be reduced gradually over a few days. Do not stop taking lofexidine suddenly, as this can cause your blood pressure to rise suddenly which could be harmful.
एक नजर में
Lofexidine is a medicine used to reduce withdrawal symptoms during opioid detoxification.
It can help reduce chills, sweating, stomach cramps, muscle pain, and sleep difficulties.
You must take lofexidine exactly as your doctor tells you as part of a detoxification programme.
Do not stop taking lofexidine suddenly; your doctor will tell you how to reduce the dose gradually.
Common side-effects include feeling dizzy or sleepy, dry mouth, slow heart rate, and low blood pressure.
Avoid alcohol while taking lofexidine as it can worsen side-effects like sleepiness.
Regular monitoring of your blood pressure and pulse rate will be necessary during treatment.
इस लेख में:
के लिए वीडियो चयन नशीली दवाओं के दुरुपयोग का उपचार
नीचे पढ़ना जारी रखें
About lofexidine
दवा का प्रकार | An alpha-adrenergic agonist medicine |
के लिए उपयोग किया जाता है | Reducing withdrawal symptoms during opioid detoxification (such as heroin, morphine or dihydrocodeine detox) |
जिसे कहा जाता है | Lucemyra® (USA), BritLofex® (UK - discontinued) |
के रूप में उपलब्ध | Tablets |
Lofexidine is a treatment for opioid drug dependence. Medicines for drug dependence are mainly used to reduce or prevent withdrawal symptoms while trying to break drug use.
Lofexidine is usually used alongside, but sometimes instead of, other medicines taken for opioid drug dependence such as methadone or buprenorphine. It helps to reduce withdrawal effects such as chills, sweating, stomach cramps, muscle pain, difficulties sleeping and runny nose.
Before taking lofexidine
सामग्री पर वापस जाएंSome medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking lofexidine it is important that your doctor knows:
यदि आप गर्भवती हैं या स्तनपान करा रही हैं।.
If you have a heart condition, or if you have had a heart attack, or if you have a heart rhythm problem such as a slow or irregular heartbeat.
If you have low blood pressure.
If you have had a stroke or 'mini-stroke' (also known as a transient ischaemic attack, or TIA).
If you are feeling depressed.
यदि आपके गुर्दे काम करने के तरीके में कोई समस्या है।.
यदि आप कोई अन्य दवाएं ले रहे हैं या उपयोग कर रहे हैं। इसमें वे सभी दवाएं शामिल हैं जो आप बिना पर्ची के खरीद सकते हैं, साथ ही हर्बल और पूरक दवाएं भी।.
यदि आपको कभी किसी दवा से एलर्जी की प्रतिक्रिया हुई है।.
नीचे पढ़ना जारी रखें
How to take lofexidine
सामग्री पर वापस जाएंLofexidine is used as part of a detoxification programme. Because each programme is tailored to meet a person's individual needs and no two detoxifications are exactly the same, it is important that you take lofexidine exactly as your doctor tells you to.
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about lofexidine, and will also provide you with a full list of the side-effects which you could experience from taking it.
Your doctor or community drug-team worker will tell you when and how often to take the tablets. It is likely that you will be asked to take four tablets over the course of the first day. Take your last dose of the day at bedtime, as this will help to reduce any problems you may have sleeping. Your dose may then be increased over the next few days. The maximum number of tablets you will be prescribed to take at any one time is 4, and the maximum number of tablets during any one day is 12.
You can take lofexidine tablets either before or after meals. Swallow the tablets whole with a drink of water.
If you forget to take a dose, take it as soon as you remember and then continue as before. Do not take two doses together to make up for a missed dose.
It is usual to take lofexidine for around 7-10 days, although sometimes a course of treatment can be for longer than this. You should not stop taking lofexidine suddenly, as this can cause your blood pressure to rise quickly which could be harmful. At the end of the treatment, your doctor will ask you to reduce your dose gradually over a few days to prevent this from happening.
अपने उपचार से अधिकतम लाभ प्राप्त करना
सामग्री पर वापस जाएंIt is important that you keep your regular appointments with your doctor/clinic so that your progress can be reviewed. Your blood pressure and pulse rate will need to be regularly monitored (especially in the first few days) to make sure you are taking a dose which helps your condition but avoids unwanted symptoms.
Lofexidine will help you to deal with withdrawal symptoms but it will not help you through cravings. You are more likely to succeed in breaking your drug habit if you have support and counselling. Local drug community teams, self-help groups and other agencies can be of help. It is much harder to 'do it alone', so go for counselling and help if it is available in your area. Try to stay positive and relaxed, drink plenty of fluids, and eat a light diet.
You should not drink alcohol while you are on lofexidine because it can increase side-effects such as feeling sleepy or dizzy.
नीचे पढ़ना जारी रखें
Can lofexidine cause problems?
सामग्री पर वापस जाएंAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains the most common ones associated with lofexidine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common lofexidine side-effects (these affect more than 1 in 10 people) | अगर मुझे यह अनुभव होता है तो मैं क्या कर सकता हूँ? |
Feeling dizzy or sleepy | If you feel dizzy, sit down for a while until you feel better. It is important you do not drive and do not use tools or machines while affected. Do not drink alcohol |
Dry mouth and throat | शुगर-फ्री गम चबाने या शुगर-फ्री मिठाई चूसने की कोशिश करें |
Slow heart rate, low blood pressure | Your doctor will check for this |
यदि आपको कोई अन्य लक्षण महसूस होते हैं जो आपको लगता है कि दवा के कारण हो सकते हैं, तो आगे की सलाह के लिए अपने डॉक्टर या फार्मासिस्ट से बात करें।.
How to store lofexidine
सामग्री पर वापस जाएंसभी दवाओं को बच्चों की पहुँच और दृष्टि से दूर रखें।.
ठंडी, सूखी जगह पर रखें, सीधे गर्मी और रोशनी से दूर।.
सभी दवाओं के बारे में महत्वपूर्ण जानकारी
सामग्री पर वापस जाएंसभी दवाओं के बारे में महत्वपूर्ण जानकारी
Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
यदि आप कोई ऑपरेशन या दंत चिकित्सा करवा रहे हैं, तो जो व्यक्ति उपचार कर रहा है उसे बताएं कि आप कौन सी दवाएं ले रहे हैं।.
यदि आप कोई दवा खरीदते हैं, तो एक फार्मासिस्ट से जांच लें कि वे आपकी अन्य दवाओं के साथ लेने के लिए सुरक्षित हैं।.
यह दवा आपके लिए है। इसे कभी भी अन्य लोगों को न दें, भले ही उनकी स्थिति आपकी जैसी ही क्यों न लगे।.
Never keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
यदि इस दवा के बारे में आपके कोई प्रश्न हैं तो अपने फार्मासिस्ट से पूछें।.
दवा या टीके के दुष्प्रभावों की रिपोर्ट करें
यदि आपको दुष्प्रभाव महसूस होते हैं, तो आप उन्हें ऑनलाइन रिपोर्ट कर सकते हैं येलो कार्ड वेबसाइट.

दवाओं को मिलाने के बारे में अनिश्चित?
दवाओं, सप्लीमेंट्स और खाद्य पदार्थों के बीच संभावित इंटरैक्शन की जांच करें, उन्हें एक साथ लेने से पहले।.
अक्सर पूछे जाने वाले प्रश्न
How quickly does lofexidine start to work to reduce withdrawal symptoms?
Lofexidine is part of a detoxification programme, and its effects on reducing withdrawal symptoms like chills, sweating, and muscle pain begin as you start taking it. The dose may be increased over the first few days to help manage these symptoms effectively.
What should I do if I forget a dose of lofexidine?
If you forget to take a dose, you should take it as soon as you remember. After that, continue with your regular dosing schedule. It's important not to take two doses together to compensate for a missed dose.
Can I drink alcohol while taking lofexidine?
No, you should not drink alcohol when you are taking lofexidine. Alcohol can worsen side-effects such as feeling sleepy or dizzy.
Will lofexidine help with drug cravings?
Lofexidine is effective in helping to manage the physical withdrawal symptoms associated with opioid detoxification. However, it will not address drug cravings. To successfully break a drug habit, it is recommended to seek support and counselling from local drug community teams, self-help groups, and other agencies.
What is the maximum amount of lofexidine I can take in one day?
The maximum number of tablets you will be prescribed to take at any one time is four, and the maximum total number of tablets you can take within a single day is twelve.
How long is a typical course of lofexidine treatment?
A typical course of lofexidine treatment usually lasts for about 7-10 days. However, in some cases, a course of treatment might be longer than this, depending on individual needs and your doctor's instructions.
Why is it important to have my blood pressure and pulse rate checked while on lofexidine?
Your blood pressure and pulse rate need to be monitored regularly, especially during the first few days of treatment. This is to ensure that the dose you are taking is effectively helping your condition while avoiding any unwanted symptoms related to potential changes in blood pressure or heart rate.
अधिक पठन और संदर्भ
- मेडिसिन्स कम्प्लीट बीएनएफ 89वां संस्करण; ब्रिटिश मेडिकल एसोसिएशन और रॉयल फार्मास्यूटिकल सोसाइटी ऑफ ग्रेट ब्रिटेन, लंदन।.
नीचे पढ़ना जारी रखें
लेखक के बारे मेंपूरा जीवन परिचय देखें

Michael Stewart, MRPharmS
दवा पत्रक समीक्षा प्रबंधक – ठेकेदार, फार्मासिस्ट
BPharm (Hons), MRPharmS
माइकल मिडलैंड्स और साउथ यॉर्कशायर में एक सामुदायिक फार्मासिस्ट हैं, जो दवाओं और चिकित्सा स्थितियों पर सलाह देने में 20 से अधिक वर्षों का अनुभव रखते हैं। उनके पास स्वास्थ्य देखभाल प्रशिक्षण में मजबूत पृष्ठभूमि है, उन्होंने फार्मेसी टीमों और आवासीय देखभाल सेटिंग्स के कर्मचारियों, जिनमें नर्सें शामिल हैं, के लिए प्रशिक्षण पाठ्यक्रम तैयार और प्रस्तुत किए हैं। उन्होंने समुदाय में कम तीव्रता वाली स्थितियों के प्रबंधन के लिए फार्मेसी सलाहकार बोर्डों में भी योगदान दिया है।.
समीक्षक के बारे में

Sid Dajani
सुल्तान दाजानी ने 1994 में लंदन स्कूल ऑफ फार्मेसी से योग्यता प्राप्त की और 1842 में इसकी स्थापना के बाद से रॉयल फार्मास्यूटिकल सोसाइटी परिषद के सबसे युवा निर्वाचित सदस्य बने।.
लेख का इतिहास
इस पृष्ठ पर दी गई जानकारी योग्य चिकित्सकों द्वारा लिखी और सहकर्मी समीक्षा की गई है।.
अगली समीक्षा की तिथि: 11 फरवरी 2028
11 Feb 2025 | नवीनतम संस्करण

पूछें, साझा करें, जुड़ें।.
चर्चाओं को ब्राउज़ करें, प्रश्न पूछें, और सैकड़ों स्वास्थ्य विषयों पर अनुभव साझा करें।.
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