मधुमेह के लिए लिक्सिसेनाटाइड

About lixisenatide

Insulin is a hormone which is made naturally in your body, in the pancreas. It helps to control the levels of sugar (glucose) in your blood. If your body does not make enough insulin, or if it does not use the insulin it makes effectively, this results in the condition called मधुमेह (डायबिटीज मेलिटस).

People with diabetes need treatment to control the amount of sugar in their blood. This is because good control of blood sugar levels reduces the risk of complications later on. Some people can control the sugar in their blood by making changes to the food they eat but, for other people, medicines are given alongside the changes in diet. Lixisenatide is one of the medicines that are prescribed for people with टाइप 2 मधुमेह.

Lixisenatide works in three ways. It increases the amount of insulin produced by your body which then reduces the level of sugar in your blood. It also reduces the amount of a substance called glucagon being produced by your pancreas. Glucagon causes your liver to produce more sugar, so by reducing the amount of glucagon in your body, this also helps to reduce the levels of sugar in your blood. Lixisenatide also works on your stomach so that food passes more slowly through it. This means that the sugar from your meals takes longer to get into your blood.

Lixisenatide is given as an injection just under the surface of the skin. It is administered using an injection device called a pre-filled pen. It is used in addition to other antidiabetic medicines.

Before taking lixisenatide

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking lixisenatide it is important that your doctor knows:

• यदि आप गर्भवती हैं, बच्चे की योजना बना रही हैं या स्तनपान करवा रही हैं।.

• If you have a problem with your stomach or digestive system.

• यदि आपके गुर्दे काम करने के तरीके में कोई समस्या है।.

• यदि आप कोई अन्य दवाएं ले रहे हैं। इसमें वे सभी दवाएं शामिल हैं जो आप बिना पर्ची के खरीद सकते हैं, साथ ही हर्बल और पूरक दवाएं भी शामिल हैं।.

• यदि आपको कभी किसी दवा से एलर्जी की प्रतिक्रिया हुई है।.

How to take lixisenatide

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack as well as any information you are given by your doctor or diabetes clinic. The manufacturer's leaflet will provide you with a full list of the side-effects which you may experience.

• Use lixisenatide exactly as your doctor tells you to. Your doctor or diabetes nurse will show you how to use the pre-filled pen to inject yourself. Lixisenatide should be injected into the skin on your upper arms, thigh, or tummy (abdomen). Try to choose a slightly different injection site for each of your injections as this will help to prevent skin problems and difficulties in injecting.

• Use lixisenatide once a day. You should use it during the hour before you eat a meal (usually before breakfast या the evening meal). Although you can choose which meal to inject before, you should use lixisenatide before the same meal on each day. You will start on a dose of 10 micrograms daily for two weeks, then the dose will be increased to 20 micrograms daily. To make this easy for you, it is likely you will be prescribed a 'treatment initiation pack' which contains a two-week supply of 10 microgram doses (green pre-filled pen) and a two-week supply of 20 micrograms (purple pre-filled pen).

• If you forget to use lixisenatide before your usual meal, use it before your next meal instead. Do not inject lixisenatide after you have eaten.

अपने उपचार से अधिकतम लाभ प्राप्त करना

• It is important that you keep your regular doctor's and clinic appointments. This is so that your progress can be monitored. You will need regular check-ups with an eye clinic and a foot clinic as well as with your doctor and diabetes clinic.

• Your doctor may recommend that you test for sugar (glucose) in your blood or urine regularly to check that your diabetes is being controlled. Your doctor or diabetes nurse will show you how to do this.

• यदि आपके डॉक्टर ने आपके आहार में बदलाव, धूम्रपान छोड़ने या नियमित व्यायाम करने के बारे में सलाह दी है, तो आपके लिए दी गई सलाह का पालन करना महत्वपूर्ण है।.

• Make sure you know what it feels like if your blood sugar is low. This is known as hypoglycaemia, or a 'hypo'. Using lixisenatide alongside insulin or other medicines for type 2 diabetes may cause low blood sugar. The first signs of hypoglycaemia are feeling shaky or anxious, sweating, looking pale, feeling hungry, having a feeling that your heart is pounding (palpitations), and feeling dizzy. If this happens, eat something containing sugar, such as dextrose tablets, jelly babies or a sugary drink (non-diet), and then follow this up with a snack such as a sandwich or a banana.

• यदि आप एक ड्राइवर हैं, तो आपको विशेष ध्यान रखना चाहिए, क्योंकि यदि आपका मधुमेह अच्छी तरह से नियंत्रित नहीं है, तो आपकी ध्यान केंद्रित करने की क्षमता प्रभावित हो सकती है। आपको यात्रा से पहले अपने रक्त शर्करा स्तर की जांच करने और लंबी यात्राओं पर अपने साथ एक नाश्ता रखने की सलाह दी जा सकती है।.

• शराब का सेवन न करें, क्योंकि यह आपके रक्त शर्करा के नियंत्रण को प्रभावित कर सकता है। यदि आपको इस बारे में और सलाह की आवश्यकता है, तो अपने डॉक्टर से पूछें।.

• If you get unusually thirsty, pass urine more frequently than normal, or feel very tired, you should let your doctor know. These are signs that there is too much sugar in your blood and your treatment may need adjusting.

• किसी भी नए शारीरिक व्यायाम को शुरू करने से पहले अपने डॉक्टर से परामर्श करें, क्योंकि इसका आपके रक्त शर्करा स्तर पर प्रभाव पड़ेगा और आपको अपने रक्त या मूत्र स्तर को अधिक नियमित रूप से जांचने की आवश्यकता हो सकती है।.

• If you are due to have an operation or dental treatment, you should tell the person carrying out the treatment that you have diabetes and give them a list of the medicines you are taking.

• This medicine should not be used during pregnancy. Women and girls of childbearing potential must use effective contraception during treatment and for two months after stopping.

• If you buy any medicines, always check with a pharmacist that they are suitable for you to take. Lixisenatide can interfere with the way some other medicines are absorbed which stops them from working properly. Because of this, some medicines should not be taken during the hour before lixisenatide is given, or during the four hours after it has been given.

• Treatment for diabetes is usually lifelong. Continue with lixisenatide unless you are told otherwise by your doctor.

Can lixisenatide cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with lixisenatide. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

If you experience any other symptoms which you think may be due to the injections, speak with your doctor or pharmacist for further advice.

How to store lixisenatide

• सभी दवाओं को बच्चों की पहुँच और दृष्टि से दूर रखें।.

• Lixisenatide can be kept for 14 days at room temperature, as long as this is below 30°C and it is kept away from direct heat and sunlight. It is, however, best to store your unopened packs in a refrigerator. Do not freeze lixisenatide.

• The pre-filled pens must be discarded 14 days after being first used.

सभी दवाओं के बारे में महत्वपूर्ण जानकारी