recombination signal binding protein for immunoglobulin kappa J region
अंतिम अद्यतन 8 सितम्बर 2025
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यह RBPJ gene provides instructions for making a protein called RBP-J, which is an integral part of a signaling pathway known as the Notch pathway. Notch signaling controls how certain types of cells develop in the growing embryo, including those that form the bones, heart, muscles, nerves, and blood. Signaling through the Notch pathway stimulates the RBP-J protein to attach (bind) to specific regions of DNA and control the activity of genes that play a role in cellular development.
Normal function
यह RBPJ gene provides instructions for making a protein called RBP-J, which is an integral part of a signaling pathway known as the Notch pathway. Notch signaling controls how certain types of cells develop in the growing embryo, including those that form the bones, heart, muscles, nerves, and blood. Signaling through the Notch pathway stimulates the RBP-J protein to attach (bind) to specific regions of DNA and control the activity of genes that play a role in cellular development.
Conditions referring to this gene or chromosome
Other names
CBF-1
CBF1
H-2K binding factor-2
IGKJRB
IGKJRB1
RBP-J
RBP-J kappa
RBP-JK
RBPJK
RBPSUH
SUH
SUH_HUMAN
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गुइलेन-बैरे सिंड्रोम
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प्रतिरक्षा प्रणाली
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एमपॉक्स वायरस
Antibodies हैं proteins made by our प्रतिरक्षा system during infection. Immunoglobulins Immunoglobulins are antibodies. These are proteins that are made by the body's immune system to fight infection. We can also make treatments for some diseases by getting these antibodies from a number of... Vaccinia immune globulin (VIG) is an immunoglobulin made.
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एंटीबॉडी और एंटीजन परीक्षण
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बॉर्नहोम रोग
Bornholm disease is an illness which causes flu-like symptoms, together with pain in the chest or tummy (abdomen). Young babies are most at risk of serious complications. Babies may need preventative treatment (immunoglobulin) to help prevent complications. What is Bornholm disease. The recommended treatment is called immunoglobulin. This is given.
Patient information leaflet
इम्यून थ्रोम्बोसाइटोपेनिक पुरपुरा
These are less often used now than they used to be. Intravenous immunoglobulin (IVIg) This is an injection of a protein into the bloodstream and has been shown to work well in about 8 in 10 children in increasing the number of platelets. It is not usually used as the first option because it involves an injection. Anti-D immunoglobulin This is.
अधिक पठन और संदर्भ
- recombination signal binding protein for immunoglobulin kappa J region; MedlinePlus, National Library of Medicine.
- Castel D, Mourikis P, Bartels SJ, Brinkman AB, Tajbakhsh S, Stunnenberg HG. Dynamic binding of RBPJ is determined by Notch signaling status. Genes Dev. 2013 May 1;27(9):1059-71. doi: 10.1101/gad.211912.112.
- Hassed SJ, Wiley GB, Wang S, Lee JY, Li S, Xu W, Zhao ZJ, Mulvihill JJ, Robertson J, Warner J, Gaffney PM. RBPJ mutations identified in two families affected by Adams-Oliver syndrome. Am J Hum Genet. 2012 Aug 10;91(2):391-5. doi: 10.1016/j.ajhg.2012.07.005.
- Zanotti S, Canalis E. Notch signaling in skeletal health and disease. Eur J Endocrinol. 2013 May 8;168(6):R95-103. doi: 10.1530/EJE-13-0115. Print 2013 Jun.
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