Can I take Aspirin and Metformin together?

Why this happens

Aspirin can make the body more sensitive to insulin and may slightly increase the amount of insulin released. When combined with metformin, this can occasionally lead to a stronger blood-sugar-lowering effect than intended.

What you should do

You can usually take these medicines together, but you should monitor your blood sugar levels more closely, especially when starting or changing the dose of aspirin. Learn to recognise signs of low blood sugar, such as feeling shaky, sweaty, hungry, or dizzy. If you notice these symptoms frequently, speak to your doctor.

Important precautions

Asthma

Do not take aspirin if you have a history of asthma triggered by aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs), as it can cause a life-threatening asthma attack.

Severe kidney disease

You must not take metformin if your kidneys are not working properly. This can lead to a rare but life-threatening build-up of lactic acid in the blood (lactic acidosis).

Children under 16 years old

Never give aspirin to children under 16 unless specifically prescribed by a doctor. It can cause Reye’s syndrome, a rare but potentially fatal condition affecting the brain and liver.

Food and drink warnings

Alcohol

Drinking alcohol while taking aspirin can increase the risk of stomach irritation and bleeding. It is best to limit alcohol intake, especially if you take aspirin regularly.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.