मुख्य सामग्री पर जाएं

फुफ्फुसीय उच्च रक्तचाप के लिए एम्ब्रिसेंटन

Volibris

Ambrisentan is used to treat high blood pressure in people who have pulmonary arterial hypertension.

The usual dose is one 5 mg tablet daily. You can take ambrisentan either with or without food.

The most common side-effects are headache, and swollen feet and ankles.

एक नजर में

  • Ambrisentan is a medicine used to treat high blood pressure in the blood vessels supplying the lungs.

  • It works by widening the blood vessels to the lungs, allowing blood to flow more easily.

  • Always take ambrisentan exactly as your specialist doctor tells you to.

  • Do not become pregnant while taking ambrisentan as it can harm an unborn baby.

  • You will need regular blood tests to check for anaemia and liver problems.

  • Common side effects include headaches and swollen feet or ankles.

About ambrisentan

दवा का प्रकार

A vasodilator antihypertensive medicine, called an endothelin receptor antagonist

के लिए उपयोग किया जाता है

Pulmonary arterial hypertension in adults

जिसे कहा जाता है

Volibris®

के रूप में उपलब्ध

Tablets

Ambrisentan is prescribed to treat pulmonary arterial hypertension (PAH). This is a condition where there is too high a blood pressure in the blood vessels that supply the lungs from the heart.

Ambrisentan relaxes the muscle cells in the walls of the blood vessels to your lungs, allowing them to become wider (dilated). This reduces the pressure in these blood vessels and allows blood to flow more easily through them. In turn, this increases the supply of blood to your lungs and improves your ability to do physical activities. It will be prescribed for you by a doctor who is a specialist.

Before taking ambrisentan

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking ambrisentan it is important that your doctor knows:

  • If you are or could become pregnant, or if you are breastfeeding.

  • If you have any problems with the way your liver works, or if you have any problems with the way your kidneys work.

  • If you have been told you have a reduced number of red blood cells (anaemia).

  • If you have been told you have a condition called idiopathic pulmonary fibrosis (IPF), where there is scarring in your lungs.

  • यदि आपको कभी किसी दवा से एलर्जी की प्रतिक्रिया हुई है।.

  • यदि आप कोई अन्य दवाएं ले रहे हैं। इसमें वे सभी दवाएं शामिल हैं जो आप बिना पर्ची के खरीद सकते हैं, साथ ही हर्बल और पूरक दवाएं भी शामिल हैं।.

How to take ambrisentan tablets

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about ambrisentan, and it will also provide you with a full list of the side-effects which you could experience from taking it.

  • Take ambrisentan exactly as your doctor tells you to. The usual dose is one 5 mg tablet daily, although your doctor may increase the strength of your tablets to 10 mg if a higher dose is needed. Unless your doctor tells you otherwise, you can generally take your dose at a time of day that suits you. You should, however, try to take each of your doses at a similar time of day, each day.

  • Swallow the tablets whole with a drink of water - do not break or chew the tablets. You can take ambrisentan tablets either with or without food.

  • If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, leave out the forgotten dose from the previous day and take the dose that is due as normal. Do not take two doses at the same time to make up for a missed dose.

अपने उपचार से अधिकतम लाभ प्राप्त करना

  • Try to keep all your regular appointments with your doctor. This is so your doctor can check on your progress. You will need to have regular blood tests while on ambrisentan to check that you do not develop anaemia. Your doctor will also want to check that your liver stays healthy. Signs that your liver may not be working properly are feeling sick, a high temperature, dark urine, jaundice, stomach pain, feeling unusually tired, and flu-like symptoms - let your doctor know straightaway if you develop any of these.

  • You must avoid getting pregnant while you are taking ambrisentan because it could cause harm to an unborn baby. Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner.

  • It is possible that ambrisentan taken long-term reduces fertility in men by lowering the sperm count. Discuss this with your doctor if you have any concerns about it.

  • If you are due to have an operation or some other medical treatment, it is important that you tell the person carrying out the treatment that you are taking ambrisentan.

  • If you buy any medicines 'over the counter', always check with a pharmacist that they are suitable for you to take with ambrisentan.

Can ambrisentan tablets cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with ambrisentan. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common

ambrisentan side-effects (these affect more than 1 in 10 people)


अगर मुझे यह अनुभव होता है तो मैं क्या कर सकता हूँ?

सिरदर्द

Drink plenty of water and ask your pharmacist to recommend a suitable painkiller. If the headaches continue, speak with your doctor

Swollen feet or ankles

If this becomes troublesome, speak with your doctor

Common

ambrisentan side-effects (these affect fewer than 1 in 10 people)

अगर मुझे यह अनुभव होता है तो मैं क्या कर सकता हूँ?

Feeling dizzy, tired or weak

Do not drive and do not use tools or machines while affected

Flushing, sinus infections, nosebleeds, feeling short of breath, a stuffy or runny nose, the sensation of having a 'thumping heart' (palpitations), chest pain

If any of these become troublesome, speak with your doctor

Feeling sick (nausea) or being sick (vomiting), stomach ache, diarrhoea

Eat simple meals - avoid fatty or spicy food. Drink plenty of water to replace lost fluids

कब्ज

Eat a healthy balanced diet and drink plenty of water

Changes to some blood tests

Your doctor will regularly check for these

If you experience any other symptoms which you think may be due to the tablets, speak with your doctor or pharmacist for further advice.

How to store ambrisentan

  • सभी दवाओं को बच्चों की पहुँच और दृष्टि से दूर रखें।.

  • ठंडी, सूखी जगह पर रखें, सीधे गर्मी और रोशनी से दूर।.

सभी दवाओं के बारे में महत्वपूर्ण जानकारी

सभी दवाओं के बारे में महत्वपूर्ण जानकारी

निर्धारित खुराक से अधिक कभी न लें। यदि आपको संदेह है कि आपने या किसी और ने इस दवा की अधिक मात्रा ले ली है, तो अपने स्थानीय अस्पताल के दुर्घटना और आपातकालीन विभाग में जाएं। कंटेनर को अपने साथ ले जाएं, भले ही वह खाली हो।.

यह दवा आपके लिए है। इसे कभी भी अन्य लोगों को न दें, भले ही उनकी स्थिति आपकी जैसी ही क्यों न लगे।.

पुरानी या अनचाही दवाइयाँ न रखें। उन्हें अपने स्थानीय फार्मेसी में ले जाएँ, जो उन्हें आपके लिए नष्ट कर देगा।.

यदि इस दवा के बारे में आपके कोई प्रश्न हैं तो अपने फार्मासिस्ट से पूछें।.

दवा या टीके के दुष्प्रभावों की रिपोर्ट करें

यदि आपको दुष्प्रभाव महसूस होते हैं, तो आप उन्हें ऑनलाइन रिपोर्ट कर सकते हैं येलो कार्ड वेबसाइट.

लक्षण जाँचकर्ता

दवाओं को मिलाने के बारे में अनिश्चित?

दवाओं, सप्लीमेंट्स और खाद्य पदार्थों के बीच संभावित इंटरैक्शन की जांच करें, उन्हें एक साथ लेने से पहले।.

अक्सर पूछे जाने वाले प्रश्न

What is pulmonary arterial hypertension (PAH)?

Pulmonary arterial hypertension (PAH) is a condition where the blood pressure in the blood vessels supplying the lungs from the heart is too high. Ambrisentan works by relaxing and widening these blood vessels, which reduces the pressure and improves blood flow to the lungs, helping with physical activities.

Are there any conditions that would prevent me from taking ambrisentan?

Yes, there are some conditions where ambrisentan might not be suitable or would require extra care. Your doctor needs to know if you are pregnant or breastfeeding, have liver or kidney problems, a reduced number of red blood cells (anaemia), a lung scarring condition called idiopathic pulmonary fibrosis (IPF), or have had an allergic reaction to any medicine.

What should I do if I forget a dose of ambrisentan?

If you forget to take a dose, take it as soon as you remember. However, if you don't remember until the following day, you should skip the forgotten dose from the previous day and take your next dose as normal. Do not take two doses at the same time to compensate for a missed dose.

Can ambrisentan affect male fertility?

It is possible that long-term use of ambrisentan could reduce fertility in men by lowering the sperm count. If you have concerns about this, you should discuss it with your doctor.

What should I do if I experience side-effects like headaches or swollen feet/ankles?

For headaches, you should drink plenty of water and can ask your pharmacist to suggest a suitable painkiller. If headaches continue, or if swollen feet or ankles become troublesome, you should speak with your doctor.

अधिक पठन और संदर्भ

लेखक के बारे मेंपूरा जीवन परिचय देखें

लेखक की छवि

हेलेन एलेन, एमफार्म

फार्मासिस्ट, चिकित्सा लेखक

MPharm

हेलेन एलेन ने 1979 में एक फार्मासिस्ट के रूप में योग्यता प्राप्त की और EMIS के लिए दवा जानकारी पत्रक की लेखिका के रूप में 3 साल बिताए।.

समीक्षक के बारे में

लेखक की छवि

Sid Dajani

सुल्तान दाजानी ने 1994 में लंदन स्कूल ऑफ फार्मेसी से योग्यता प्राप्त की और 1842 में इसकी स्थापना के बाद से रॉयल फार्मास्यूटिकल सोसाइटी परिषद के सबसे युवा निर्वाचित सदस्य बने।.

लेख का इतिहास

इस पृष्ठ पर दी गई जानकारी योग्य चिकित्सकों द्वारा लिखी और सहकर्मी समीक्षा की गई है।.

  • Next review due: 8 Jul 2027
  • 9 Jan 2023 | नवीनतम संस्करण

    द्वारा अंतिम अपडेट

    Michael Stewart, MRPharmS

    द्वारा सहकर्मी समीक्षा की गई

    Sid Dajani
  • 5 Oct 2013 | मूल रूप से प्रकाशित

    द्वारा लिखित:

    हेलेन एलेन, एमफार्म
फ्लू पात्रता जाँचकर्ता

पूछें, साझा करें, जुड़ें।.

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