मुख्य सामग्री पर जाएं

पैलिपेरिडोन दीर्घकालिक इंजेक्शन

Xeplion, Trevicta, Byannli

Paliperidone long-acting injection will be given to you by your doctor or nurse every four weeks to begin with.

If you miss an appointment for an injection, please make another appointment as soon as possible.

The most common side-effects are headache and difficulties sleeping.

एक नजर में

  • Paliperidone is an antipsychotic medicine given as a long-acting injection.

  • It is used for adults with schizophrenia to help regulate brain chemicals and control symptoms.

  • Injections are given regularly, typically once a month, with 3-monthly and 6-monthly options available.

  • Benefits include not having to remember to take daily tablets.

  • Keep all regular appointments for your injections and monitoring.

  • Tell your doctor if you are pregnant, have a heart condition, or other specified health issues.

  • Do not drink alcohol while on paliperidone as it increases the risk of side-effects.

About paliperidone long-acting injection

दवा का प्रकार

An antipsychotic medicine

के लिए उपयोग किया जाता है

Schizophrenia in adults

जिसे कहा जाता है

Xeplion®; Trevicta®; Byannli®

के रूप में उपलब्ध

Long-acting intramuscular depot injection

स्किज़ोफ्रेनिया is a mental health condition that causes disordered ideas, beliefs and experiences. You will have been prescribed paliperidone to relieve the symptoms of schizophrenia. Such symptoms include hearing, seeing, or sensing things that are not real, having mistaken beliefs and feeling unusually suspicious. Paliperidone works on the balance of chemical substances in your brain to help control these types of symptoms.

Long-acting or 'depot' injections are used for maintenance once your symptoms have been eased by taking tablets. The injection slowly releases paliperidone into your body. You will need to receive the injection regularly, once every month. A three-monthly injection (Trevicta®) is available for people who are stable on once-monthly injections. There is also a six-monthly injection (Byannli®). The main advantage of a depot injection is that you do not have to remember to take tablets every day.

Before having paliperidone injection

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start having paliperidone injections, it is important that your doctor knows:

  • यदि आप गर्भवती हैं या स्तनपान करा रही हैं।.

  • If you have a heart condition or blood vessel disease.

  • If you have liver, kidney, or prostate problems.

  • If you have any problems with your breathing.

  • If you have any of the following: epilepsy, अवसाद, पार्किंसन रोग, raised pressure in your eye (glaucoma) or a condition which causes muscle weakness, called myasthenia gravis.

  • If you have ever had yellowing of your skin or the whites of your eyes (jaundice) or a blood disorder.

  • If you are scheduled to have eye cataract surgery.

  • If you have a tumour on your adrenal gland (a condition called phaeochromocytoma), or if you have been told you have 'a prolactin-dependent tumour'.

  • If you have had an allergic reaction to a medicine.

  • यदि आप कोई अन्य दवाएं ले रहे हैं या उपयोग कर रहे हैं। इसमें वे सभी दवाएं शामिल हैं जो आप बिना पर्ची के खरीद सकते हैं, साथ ही हर्बल और पूरक दवाएं भी।.

How paliperidone long-acting injection is given

  • Before you start the treatment, ask to read the manufacturer's printed information leaflet from inside the pack. It will give you more information about paliperidone and it will also provide you with a full list of the side-effects which you may experience from having it.

  • Paliperidone injection will be given to you by your doctor or nurse. The first two doses will be injected into a muscle in your upper arm. After this, the injections can either be given into a muscle in your arm, or if preferred, the buttocks.

  • If you haven't received paliperidone injection before, you will initially be given a dose of 150 mg and then a dose of 100 mg a week later. From then on, you will need to have one injection each month. Your doctor will adjust the amount of paliperidone given to suit what is right for you.

  • When your dose of once-monthly injection is stabilised, a three-monthly injection is available and may be suitable for you.

अपने उपचार से अधिकतम लाभ प्राप्त करना

  • Your treatment will require careful monitoring to make sure that you get the best possible benefit from paliperidone. Keep your regular doctor's appointments so that you get your injections on time and your progress can be checked. If you miss an appointment for an injection, contact your doctor to arrange for another appointment as soon as possible. This is so that you can be given the injection without any further delay.

  • If you are due to have any dental treatment or an operation, please tell the person carrying out the treatment that you have had a paliperidone injection. This is important because it may interfere with any anaesthetic you receive. If you are having cataract surgery, it is particularly important that you tell your surgeon that you are on paliperidone. This is because an eye problem known as 'floppy iris syndrome' has developed in some people and your doctor will want to advise you about the risks of this.

  • If you buy or take any 'over-the-counter' medicines, check with a pharmacist that they are suitable for you to take with paliperidone.

  • If you have diabetes you may need to check your blood glucose more frequently, as paliperidone may affect the levels of sugar in your blood. Your doctor will advise you about this.

  • If you drink alcohol, please ask your doctor for advice. Alcohol increases the risk of side-effects from paliperidone, so it is best avoided.

Can paliperidone cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with paliperidone long-acting injection. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common paliperidone injection side-effects (these affect more than 1 in 10 people)

अगर मुझे यह अनुभव होता है तो मैं क्या कर सकता हूँ?

Difficulties sleeping

Discuss this with your doctor if it becomes troublesome

सिरदर्द

बहुत सारा पानी पिएं और अपने फार्मासिस्ट से उपयुक्त दर्द निवारक की सिफारिश करने के लिए कहें। यदि सिरदर्द जारी रहता है, तो अपने डॉक्टर को सूचित करें

Common paliperidone injection side-effects (these affect fewer than 1 in 10 people)

अगर मुझे यह अनुभव होता है तो मैं क्या कर सकता हूँ?

Pain at the site of the injection

This should quickly pass. If the area becomes red, swollen or 'lumpy', let your doctor know

Feeling dizzy, tired or sleepy

Do not drive and do not use tools or machines. Do not drink alcohol

Feeling shaky or restless, unusual or uncontrollable movements

Speak with your doctor

Feeling sick (nausea) or being sick (vomiting), indigestion, tummy (abdominal) discomfort

Stick to simple meals - avoid rich or spicy food

दस्त

Drink plenty of water to replace lost fluids

कब्ज

Drink plenty of water and eat a well-balanced diet

Increased infections, weight increase or loss, mood changes, high blood pressure, toothache, rash, aches and pains

यदि इनमें से कोई भी समस्या उत्पन्न करता है, तो अपने डॉक्टर से इस पर चर्चा करें

Changes to the results of some medical tests

Your doctor will check for these

Important: if you experience symptoms such as muscle stiffness, a very high temperature (fever), feeling confused, a fast heartbeat and sweating, you should contact your doctor immediately. These can be signs of a rare but serious condition known as neuroleptic malignant syndrome.

मैंf you experience any other symptoms which you think may be due to the medicine, please speak with your doctor or pharmacist for further advice.

How to store paliperidone

  • सभी दवाओं को बच्चों की पहुँच और दृष्टि से दूर रखें।.

  • ठंडी, सूखी जगह पर रखें, सीधे गर्मी और रोशनी से दूर।.

सभी दवाओं के बारे में महत्वपूर्ण जानकारी

सभी दवाओं के बारे में महत्वपूर्ण जानकारी

If you suspect that you have had an overdose of this medicine, contact your doctor or go to the accident and emergency department of your local hospital.

यदि इस दवा के बारे में आपके कोई प्रश्न हैं तो अपने फार्मासिस्ट से पूछें।.

दवा या टीके के दुष्प्रभावों की रिपोर्ट करें

यदि आपको दुष्प्रभाव महसूस होते हैं, तो आप उन्हें ऑनलाइन रिपोर्ट कर सकते हैं येलो कार्ड वेबसाइट.

लक्षण जाँचकर्ता

दवाओं को मिलाने के बारे में अनिश्चित?

दवाओं, सप्लीमेंट्स और खाद्य पदार्थों के बीच संभावित इंटरैक्शन की जांच करें, उन्हें एक साथ लेने से पहले।.

अक्सर पूछे जाने वाले प्रश्न

What should I do if I miss an appointment for my paliperidone injection?

It is important to contact your doctor as soon as possible to reschedule your appointment if you miss one. This ensures you receive your injection without further delay, which is crucial for the effectiveness of the treatment.

Are there any specific concerns if I have diabetes and am taking paliperidone?

Yes, if you have diabetes, you might need to check your blood glucose levels more often. Paliperidone can affect your blood sugar, so your doctor will provide specific advice on how to manage this while on the medication.

Can I take other medications, including over-the-counter or herbal remedies, while on paliperidone?

Before taking any other medicines, including those available without a prescription, or any herbal and complementary medicines, you should check with a pharmacist to ensure they are suitable to take with paliperidone. Some medications can interact negatively.

What is 'floppy iris syndrome' and why is it important to tell my surgeon about paliperidone before cataract surgery?

'Floppy iris syndrome' is an eye problem that has been observed in some people taking paliperidone. If you are having cataract surgery, it is particularly important to inform your surgeon about your medication so they can advise you on the potential risks and take necessary precautions during the procedure.

What should I do if I think I'm experiencing Neuroleptic Malignant Syndrome?

If you experience symptoms like muscle stiffness, a very high temperature (fever), confusion, a fast heartbeat, and sweating, you should contact your doctor immediately. These could be signs of a rare but serious condition called neuroleptic malignant syndrome.

अधिक पठन और संदर्भ

लेखक के बारे मेंपूरा जीवन परिचय देखें

लेखक की छवि

Michael Stewart, MRPharmS

दवा पत्रक समीक्षा प्रबंधक – ठेकेदार, फार्मासिस्ट

BPharm (Hons), MRPharmS

माइकल मिडलैंड्स और साउथ यॉर्कशायर में एक सामुदायिक फार्मासिस्ट हैं, जो दवाओं और चिकित्सा स्थितियों पर सलाह देने में 20 से अधिक वर्षों का अनुभव रखते हैं। उनके पास स्वास्थ्य देखभाल प्रशिक्षण में मजबूत पृष्ठभूमि है, उन्होंने फार्मेसी टीमों और आवासीय देखभाल सेटिंग्स के कर्मचारियों, जिनमें नर्सें शामिल हैं, के लिए प्रशिक्षण पाठ्यक्रम तैयार और प्रस्तुत किए हैं। उन्होंने समुदाय में कम तीव्रता वाली स्थितियों के प्रबंधन के लिए फार्मेसी सलाहकार बोर्डों में भी योगदान दिया है।.

समीक्षक के बारे में

लेखक की छवि

Sid Dajani

सुल्तान दाजानी ने 1994 में लंदन स्कूल ऑफ फार्मेसी से योग्यता प्राप्त की और 1842 में इसकी स्थापना के बाद से रॉयल फार्मास्यूटिकल सोसाइटी परिषद के सबसे युवा निर्वाचित सदस्य बने।.

लेख का इतिहास

इस पृष्ठ पर दी गई जानकारी योग्य चिकित्सकों द्वारा लिखी और सहकर्मी समीक्षा की गई है।.

  • Next review due: 24 Aug 2027
  • 17 Aug 2024 | नवीनतम संस्करण

    द्वारा अंतिम अपडेट

    Michael Stewart, MRPharmS

    द्वारा सहकर्मी समीक्षा की गई

    Sid Dajani
फ्लू पात्रता जाँचकर्ता

पूछें, साझा करें, जुड़ें।.

चर्चाओं को ब्राउज़ करें, प्रश्न पूछें, और सैकड़ों स्वास्थ्य विषयों पर अनुभव साझा करें।.

पेशेंट न्यूज़लेटर के लिए साइन अप करें

आपकी साप्ताहिक खुराक स्पष्ट, विश्वसनीय स्वास्थ्य सलाह की - जो आपको सूचित, आत्मविश्वासी और नियंत्रण में महसूस करने में मदद करने के लिए लिखी गई है।.

कृपया एक मान्य ईमेल पता दर्ज करें

सदस्यता लेने पर आप हमारी स्वीकार करते हैं गोपनीयता नीति. आप किसी भी समय सदस्यता समाप्त कर सकते हैं। हम कभी भी आपका डेटा नहीं बेचते।.