Duloxetine for urinary symptoms
Yentreve
द्वारा सहकर्मी समीक्षा की गई Sid Dajaniद्वारा अंतिम अपडेट Michael Stewart, MRPharmSअंतिम अद्यतन 23 Aug 2024
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The brand of duloxetine called Yentreve® is prescribed for women with stress incontinence. Take one capsule twice daily, in the morning and late afternoon. You may be given generic duloxetine capsules; 20 mg and 40 mg capsules are prescribed for stress incontinence.
Remember to do the exercises you have been given to strengthen your pelvic floor muscles.
Each time you collect a new supply of capsules, make sure the strength (20 mg or 40 mg) is the same as you have taken previously. If not, please speak with your pharmacist who will advise you.
एक नजर में
Duloxetine (Yentreve) treats stress incontinence in women when other treatments have not worked.
It helps bladder muscles contract more strongly to control urine flow.
Take capsules as prescribed, usually twice daily, with or without food.
Common side-effects include feeling sick, dry mouth, and constipation.
Do not stop duloxetine suddenly as it can cause problems.
If you have distressing thoughts or signs of serotonin syndrome, contact your doctor.
इस लेख में:
के लिए वीडियो चयन जनन-मूत्र संबंधी चिकित्सा
नीचे पढ़ना जारी रखें
About duloxetine for urinary symptoms
दवा का प्रकार | A serotonin and noradrenaline reuptake inhibitor |
के लिए उपयोग किया जाता है | Symptoms of stress incontinence in women |
जिसे कहा जाता है | Yentreve® |
के रूप में उपलब्ध | Capsules |
Stress incontinence is the most common form of incontinence. It means you pass urine with things like coughing, sneezing or exercise. It happens when the pelvic floor muscles that support your bladder are weakened. Childbirth is a common reason for a weak pelvic floor. The main treatment for stress incontinence is pelvic floor exercises. Surgery to tighten or support your bladder outlet can also help.
Duloxetine may be advised if pelvic floor exercises alone are not helping to treat your stress incontinence. It is usually advised in women who do not want to undergo surgery, or in women who have health problems that may mean that surgery is unsuitable.
Duloxetine is thought to work by interfering with certain chemicals (called serotonin and noradrenaline) that are used within the nerves that send messages to your pelvic floor muscles. This helps the muscles around the bladder outlet to contract more strongly, and this in turn controls the flow of urine and helps to prevent any leakage.
Duloxetine is also prescribed for the treatment of some mood and nerve disorders, although a different brand and strength of capsule are used. There is a separate medicine leaflet called Duloxetine for mood and nerve disorders which gives more information about duloxetine when it is used for this type of condition.
Before taking duloxetine
सामग्री पर वापस जाएंSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking duloxetine it is important that your doctor knows:
If you are pregnant, trying for a baby or breastfeeding.
If you have any problems with the way your liver works, or any problems with the way your kidneys work.
If you have a heart condition.
If you have increased eye pressure (called glaucoma).
If you have high blood pressure.
If you have ever had 'high' moods, such as mania in bipolar disorder.
If you have ever had a fit (seizure).
If you have a blood disorder that increases your risk of bleeding.
यदि आप कोई अन्य दवाएं ले रहे हैं या उपयोग कर रहे हैं। इसमें वे सभी दवाएं शामिल हैं जो आप बिना पर्ची के खरीद सकते हैं, साथ ही हर्बल और पूरक दवाएं भी।.
यदि आपको कभी किसी दवा से एलर्जी की प्रतिक्रिया हुई है।.
नीचे पढ़ना जारी रखें
How to take duloxetine
सामग्री पर वापस जाएंBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about duloxetine and will provide you with a full list of the side-effects which you may experience from taking it.
Take duloxetine exactly as your doctor tells you to. The usual dose is one 40 mg capsule twice daily (in the morning and late afternoon). If you are taking duloxetine for the first time, your doctor may give you the lower 20 mg strength capsule for a couple of weeks - this is to help avoid any unwanted symptoms when you first take duloxetine.
Try to take your doses at the same times of day each day, as this will help you to remember to take your doses regularly. You can take duloxetine either before or after meals. Take the capsules with a drink of water to help you to swallow.
If you forget to take a dose at your usual time, take it when you remember. However, if it is nearly time to take your next dose when you remember then leave out the forgotten dose and take your next dose when it is due. Do not take two doses together to make up for a missed dose.
अपने उपचार से अधिकतम लाभ प्राप्त करना
सामग्री पर वापस जाएंअपने डॉक्टर के साथ अपनी नियमित नियुक्तियों को बनाए रखने का प्रयास करें। यह इसलिए है ताकि आपका डॉक्टर आपकी प्रगति की जांच कर सके और आपके उपचार की समीक्षा कर सके।.
Remember to do the exercises you have been given to strengthen your pelvic floor muscles. This is important because the majority of people with stress incontinence are much improved with these exercises.
If you have been advised to reduce your weight, try to stick to the advice you have been given about your diet. Losing even a modest amount of weight can help to improve your symptoms.
Smoking can cause coughing which can aggravate your symptoms. It would help to not smoke. If you are a smoker and you need help to quit, ask your doctor or pharmacist for advice.
Drinking alcohol can increase the risk of unwanted effects from duloxetine, such as dizziness and blurred vision.
If you buy any medicines, check with a pharmacist that they are suitable to take with duloxetine. This is because some herbal medicines (such as St John's wort) can increase the chance that you will experience unwanted effects.
If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking duloxetine.
Keep taking duloxetine until your doctor tells you otherwise. Stopping suddenly can cause problems and your doctor may want you to reduce your dose gradually when this becomes necessary.
नीचे पढ़ना जारी रखें
Can duloxetine cause problems?
सामग्री पर वापस जाएंAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the common ones associated with duloxetine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common duloxetine side-effects (these affect more than 1 in 10 people) | अगर मुझे यह अनुभव होता है तो मैं क्या कर सकता हूँ? |
Feeling sick (nausea) | साधारण भोजन खाएं - भारी या मसालेदार भोजन से बचें |
मुंह सूखना | शुगर-फ्री गम चबाने या शुगर-फ्री मिठाई चूसने की कोशिश करें |
कब्ज | प्रत्येक दिन संतुलित आहार लेने और कई गिलास पानी पीने का प्रयास करें |
Common duloxetine side-effects (these affect fewer than 1 in 10 people) | अगर मुझे यह अनुभव होता है तो मैं क्या कर सकता हूँ? |
Blurred vision, feeling tired, dizzy or sleepy | Do not drive and do not use tools or machines while affected. Avoid alcohol |
दस्त | Drink plenty of water to replace lost fluids |
सिरदर्द | Ensure you are drinking the recommended amount of fluids each day. Ask your pharmacist to recommend a suitable painkiller. If the headaches continue, let your doctor know |
Lack of appetite, indigestion, stomach pain, flushing, increased blood pressure, difficulty sleeping, feeling anxious, skin tinglings, feeling shaky, reduced interest in sex, increased sweating | यदि इनमें से कोई भी समस्या उत्पन्न करता है, तो अपने डॉक्टर से इस पर चर्चा करें |
Important: if you develop any depressing or distressing thoughts or ideas, you should let your doctor know about this as soon as possible. When this medicine is prescribed for people with depression or anxiety, it can increase the risk of suicidal thoughts, particularly when the treatment is first started.
On rare occasions, medicines that affect the level of serotonin in the brain can cause it to go too high and cause problems. The risk is higher if you are taking another medicine with this effect (such as an antidepressant). Seek medical attention if you develop any combination of the following:
Stiff muscles or 'jerky' movements.
Unusually fast heartbeat.
High temperature (fever).
Feeling sick (nausea) or being sick (vomiting), diarrhoea.
Feeling delirious or seeing visions (hallucinating).
If you experience any other symptoms which you think may be due to the capsules, please speak with your doctor or pharmacist for further advice.
How to store duloxetine
सामग्री पर वापस जाएंसभी दवाओं को बच्चों की पहुँच और दृष्टि से दूर रखें।.
ठंडी, सूखी जगह पर रखें, सीधे गर्मी और रोशनी से दूर।.
सभी दवाओं के बारे में महत्वपूर्ण जानकारी
सामग्री पर वापस जाएंसभी दवाओं के बारे में महत्वपूर्ण जानकारी
निर्धारित खुराक से अधिक कभी न लें। यदि आपको संदेह है कि आपने या किसी और ने इस दवा की अधिक मात्रा ले ली है, तो अपने स्थानीय अस्पताल के दुर्घटना और आपातकालीन विभाग में जाएं। कंटेनर को अपने साथ ले जाएं, भले ही वह खाली हो।.
यह दवा आपके लिए है। इसे कभी भी अन्य लोगों को न दें, भले ही उनकी स्थिति आपकी जैसी ही क्यों न लगे।.
पुरानी या अनचाही दवाइयाँ न रखें। उन्हें अपने स्थानीय फार्मेसी में ले जाएँ, जो उन्हें आपके लिए नष्ट कर देगा।.
यदि इस दवा के बारे में आपके कोई प्रश्न हैं तो अपने फार्मासिस्ट से पूछें।.
दवा या टीके के दुष्प्रभावों की रिपोर्ट करें
यदि आपको दुष्प्रभाव महसूस होते हैं, तो आप उन्हें ऑनलाइन रिपोर्ट कर सकते हैं येलो कार्ड वेबसाइट.

दवाओं को मिलाने के बारे में अनिश्चित?
दवाओं, सप्लीमेंट्स और खाद्य पदार्थों के बीच संभावित इंटरैक्शन की जांच करें, उन्हें एक साथ लेने से पहले।.
अक्सर पूछे जाने वाले प्रश्न
How long will I need to take duloxetine for stress incontinence?
You should continue to take duloxetine for as long as your doctor advises. Stopping the medication suddenly can cause problems, so your doctor will likely want you to reduce your dose gradually when it's time to stop.
What should I do if I forget to take a dose of duloxetine?
If you forget a dose, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed dose and just take your next dose as usual. Do not take a double dose to make up for a forgotten one.
Can I drink alcohol while taking duloxetine?
Drinking alcohol can increase the risk of experiencing unwanted side-effects from duloxetine, such as dizziness and blurred vision. It's best to avoid alcohol if possible while on this medication.
Are there any over-the-counter medicines or herbal remedies I should avoid while taking duloxetine?
Yes, some medicines, including certain herbal remedies like St John's wort, can increase the chance of experiencing unwanted effects when taken with duloxetine. Always check with a pharmacist before buying any new medicines.
What is Serotonin Syndrome and what should I do if I think I have it?
Serotonin syndrome is a rare condition where the level of serotonin in the brain becomes too high. This can be more likely if you're taking another medicine that affects serotonin. Seek medical attention immediately if you develop symptoms such as stiff or jerky muscles, unusually fast heartbeat, high temperature, feeling sick or being sick, diarrhoea, feeling delirious, or seeing visions.
Will duloxetine definitely cure my stress incontinence?
Duloxetine helps the muscles around the bladder outlet contract more strongly to control urine flow and prevent leakage, especially when pelvic floor exercises alone aren't enough. It's often advised for women who don't want surgery or for whom surgery isn't suitable. Remember to continue your pelvic floor exercises as they significantly help most people with stress incontinence.
अधिक पठन और संदर्भ
- Manufacturer's PIL, Yentreve® 20 mg and 40 mg hard gastro-resistant capsules; Eli Lilly and Company Ltd, The electronic Medicines Compendium. Dated June 2024.
- मेडिसिन्स कम्प्लीट बीएनएफ 89वां संस्करण; ब्रिटिश मेडिकल एसोसिएशन और रॉयल फार्मास्यूटिकल सोसाइटी ऑफ ग्रेट ब्रिटेन, लंदन।.
नीचे पढ़ना जारी रखें
लेखक के बारे मेंपूरा जीवन परिचय देखें

Michael Stewart, MRPharmS
दवा पत्रक समीक्षा प्रबंधक – ठेकेदार, फार्मासिस्ट
BPharm (Hons), MRPharmS
माइकल मिडलैंड्स और साउथ यॉर्कशायर में एक सामुदायिक फार्मासिस्ट हैं, जो दवाओं और चिकित्सा स्थितियों पर सलाह देने में 20 से अधिक वर्षों का अनुभव रखते हैं। उनके पास स्वास्थ्य देखभाल प्रशिक्षण में मजबूत पृष्ठभूमि है, उन्होंने फार्मेसी टीमों और आवासीय देखभाल सेटिंग्स के कर्मचारियों, जिनमें नर्सें शामिल हैं, के लिए प्रशिक्षण पाठ्यक्रम तैयार और प्रस्तुत किए हैं। उन्होंने समुदाय में कम तीव्रता वाली स्थितियों के प्रबंधन के लिए फार्मेसी सलाहकार बोर्डों में भी योगदान दिया है।.
समीक्षक के बारे में

Sid Dajani
सुल्तान दाजानी ने 1994 में लंदन स्कूल ऑफ फार्मेसी से योग्यता प्राप्त की और 1842 में इसकी स्थापना के बाद से रॉयल फार्मास्यूटिकल सोसाइटी परिषद के सबसे युवा निर्वाचित सदस्य बने।.
लेख का इतिहास
इस पृष्ठ पर दी गई जानकारी योग्य चिकित्सकों द्वारा लिखी और सहकर्मी समीक्षा की गई है।.
Next review due: 24 Aug 2027
23 Aug 2024 | नवीनतम संस्करण

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