Simvastatin

About simvastatin

Lipids, or fats, are made naturally in your body from the food you eat. They are easily stored in your body and serve as a source of energy. कोलेस्ट्रॉल and triglycerides are types of lipid. If the concentration of these lipids in your blood becomes too high, it leads to a condition called हाइपरलिपिडेमिया. If it is the concentration of cholesterol which has become too high, it is called हाइपरकोलेस्ट्रोलेमिया. Although a high blood concentration of lipids will not make you feel ill, it can cause a problem if it is left untreated.

People with high lipid levels can develop small fatty patches called एथेरोमा. These patches develop when excess fat is deposited on to the walls of blood vessels. Over time, these patches can make a blood vessel narrower and this is called atherosclerosis (sometimes referred to as 'hardening of the arteries'). The narrowing reduces the blood flow through the artery and increases the risk of a number of heart and blood vessel diseases, such as दिल का दौरा और स्ट्रोक.

Simvastatin belongs to a group of medicines known as statins (or HMG-CoA reductase inhibitors). It regulates the amount of cholesterol and other lipids made by your body. It does this by blocking the action of a certain enzyme (called HMG-CoA reductase) which your body needs to make the fats. This lowers your risk of heart and blood vessel disease. It can also reduce this risk, even if your cholesterol levels are normal, if you are at an increased risk of heart disease as a result of other healthcare problems (such as if you have diabetes mellitus).

Before taking simvastatin

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking simvastatin it is important that your doctor knows:

• यदि आप गर्भवती हैं, बच्चे की योजना बना रही हैं या स्तनपान करवा रही हैं।.

• यदि आपके जिगर के काम करने के तरीके में कोई समस्या है, या यदि आपको कभी कोई ऐसी बीमारी हुई है जिसने आपके जिगर को प्रभावित किया है।.

• यदि आपकी थायरॉयड ग्रंथि कम सक्रिय है।.

• If you have a problem with unexplained muscle aches or pains, or if you (or a close relative) have ever had a muscle disorder.

• यदि आप नियमित रूप से बड़ी मात्रा में शराब पीते हैं।.

• यदि आपके गुर्दे काम करने के तरीके में कोई समस्या है।.

• यदि आपको कभी किसी दवा से एलर्जी की प्रतिक्रिया हुई है।.

• If you are taking any other medicines. This is particularly important because there are a number of medicines that should not be taken with simvastatin, and there are also some medicines that will affect the dose of simvastatin that your doctor prescribes for you. Please also make sure that your doctor knows of any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.

How to take simvastatin

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about simvastatin and will provide you with a full list of the side-effects which you may experience from taking it.

• Take one dose of simvastatin each day, in the evening. There are several different strengths of tablet available (10 mg, 20 mg, 40 mg and 80 mg) - your doctor will tell you which strength of tablet is right for you. Swallow the tablet with a drink of water. If you have any difficulties swallowing, let your doctor know about this as a liquid medicine may be more suitable for you.

• You can take simvastatin before or after food.

• Do not drink grapefruit juice at any time while you are taking simvastatin. This is because a chemical in grapefruit juice increases the amount of simvastatin in your bloodstream. This makes side-effects more likely and increases the risk of them being more serious.

• If you forget to take a dose, leave out the missed dose but make sure that you remember to take your next dose on the following evening. Do not take two doses together to make up for a forgotten dose.

अपने उपचार से अधिकतम लाभ प्राप्त करना

• Try to keep your regular appointments with your doctor. This is so that your doctor can check on your progress. You will need to have some blood tests from time to time. These are to measure your lipid levels and also to check that your liver has not been affected by taking simvastatin.

• आपका डॉक्टर आपको स्वस्थ आहार खाने, आमतौर पर पीने वाले शराब की मात्रा कम करने, अपने आहार में नमक की मात्रा घटाने, धूम्रपान छोड़ने और नियमित व्यायाम करने के बारे में सलाह देगा। इस सलाह का पालन करने से आपको हृदय और रक्त वाहिका रोग विकसित होने के जोखिम को कम करने में भी मदद मिलेगी।.

• Women taking simvastatin must avoid getting pregnant. Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner.

• Treatment with simvastatin is usually long-term unless you experience an adverse effect. You should continue to take it regularly.

Can simvastatin cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the side-effects associated with simvastatin, although these tend to occur only rarely and are usually mild in nature. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

If you experience any other symptoms which you think may be due to simvastatin, speak with your doctor or pharmacist for further advice.

How to store simvastatin

• सभी दवाओं को बच्चों की पहुँच और दृष्टि से दूर रखें।.

• ठंडी, सूखी जगह पर रखें, सीधे गर्मी और रोशनी से दूर।.

• The oral liquid medicine may be used for one month once the bottle has been opened. After this time, get a fresh supply.

सभी दवाओं के बारे में महत्वपूर्ण जानकारी