सोडियम क्लोड्रोनेट
Clasteon, Loron 520
द्वारा सहकर्मी समीक्षा की गई Sid Dajaniद्वारा अंतिम अपडेट Michael Stewart, MRPharmSअंतिम अद्यतन 7 Aug 2023
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Do not eat food or have drinks containing milk during the two hours before you take a dose of sodium clodronate, or for one hour after taking a dose.
Do not let yourself become dehydrated - drink several large glassfuls of water each day.
If you buy any medicines or health remedies, you should ask a pharmacist to advise you. Some mineral preparations and antacid medicines will prevent sodium clodronate from working properly.
एक नजर में
Sodium clodronate is a bisphosphonate used for bone pain in cancer and to reduce high blood calcium caused by cancer.
It works by reducing bone breakdown, which strengthens bones and lowers calcium in the blood.
Take doses exactly as prescribed, often on an empty stomach, avoiding food and other medicines for specific times.
Maintain good hydration and dental hygiene while taking this medicine.
Speak to your doctor if you experience thigh, hip, or groin pain, a loose tooth, jaw pain, or ear problems.
About sodium clodronate
दवा का प्रकार | Bisphosphonate |
के लिए उपयोग किया जाता है | Bone pain in cancer; and to reduce high blood levels of calcium caused by cancer |
जिसे कहा जाता है | Clodronate disodium (in US); Clasteon®; Loron 520® |
के रूप में उपलब्ध | Tablets and capsules |
Sodium clodronate is a bisphosphonate and is prescribed for problems which affect bones. It is prescribed to ease bone pain in people with cancer that has spread into the bone, and also to reduce hypercalcaemia associated with some cancers.
In some cancers there can be an excessive breakdown of bone. As this happens, calcium is lost from the bone and seeps into the blood, leading to higher than normal levels of calcium in the blood. This is called hypercalcaemia. Sodium clodronate binds to bone and reduces the rate at which it is broken down. This helps to strengthen bones and prevents the loss of calcium. This in turn reduces the high levels of calcium in the blood.
Before taking sodium clodronate
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking sodium clodronate it is important that your doctor knows:
यदि आप गर्भवती हैं या स्तनपान करा रही हैं।.
If you have recently had any inflammation of your digestive system such as an upset stomach or bowel.
If you are due to have any dental treatment in the near future, or if you have नहीं recently had a dental check-up.
यदि आपके गुर्दे काम करने के तरीके में कोई समस्या है।.
यदि आप कोई अन्य दवाएं ले रहे हैं। इसमें वे सभी दवाएं शामिल हैं जो आप बिना पर्ची के खरीद सकते हैं, साथ ही हर्बल और पूरक दवाएं भी शामिल हैं।.
यदि आपको कभी किसी दवा से एलर्जी की प्रतिक्रिया हुई है।.
How to take sodium clodronate
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about sodium clodronate and will provide you with a full list of the side-effects which you may experience from taking it.
Take sodium clodronate tablets/capsules exactly as your doctor tells you to. It is usual to be prescribed one or two doses to take each day. If you are prescribed one dose to take each day, take it first thing in the morning an hour before you have breakfast. If you are prescribed two doses a day, take your first dose an hour before breakfast and then take your second dose between meals (but see also the following advice).
Some foods and other medicines can interfere with how your body absorbs sodium clodronate and this will prevent the medicine from working as it should. Do not eat anything during the two hours before you take a dose, and also for one hour after taking a dose. It is particularly important that you avoid milk (including any drinks which contain milk) during this three-hour period. If you take other medicines, see the advice in the section below.
Try to take your doses of sodium clodronate at the same times of day each day. This will get you into a good daily routine and will help you avoid missing any doses.
If you do forget to take a dose, just take your next tablet/capsule at the usual time and continue as before. Do not take two doses together to make up for a missed dose.
अपने उपचार से अधिकतम लाभ प्राप्त करना
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You will need to have regular blood tests during treatment.
It is important that you do not become dehydrated during treatment with sodium clodronate. Your doctor will likely advise you to drink several large glassfuls of water each day. This is especially important in warm weather.
If you are taking any other medicines, do not take them during the two hours before you take sodium clodronate and wait for at least an hour afterwards before you take your other medicines. If you buy any medicines 'over the counter', check with a pharmacist that they are suitable for you to take. This is because mineral supplements, iron preparations, and some indigestion remedies reduce the amount of sodium clodronate which your body absorbs and this will make your treatment less effective. Also, some painkillers called non-steroidal anti-inflammatory drugs (NSAIDs), can cause kidney problems when taken alongside sodium clodronate.
Good dental hygiene is particularly important while you are taking sodium clodronate - brush your teeth regularly and remember to have routine dental check-ups. Also, tell your dentist that you are taking sodium clodronate, as some dental treatments may not be recommended for you.
Can sodium clodronate cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with sodium clodronate. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common sodium clodronate side-effects (these affect fewer than 1 in 10 people) | अगर मुझे यह अनुभव होता है तो मैं क्या कर सकता हूँ? |
Feeling sick (nausea) or being sick (vomiting) | Stick to simple foods - avoid rich or spicy meals. If this becomes troublesome, speak with your doctor |
दस्त | Drink plenty of water to replace any lost fluids. If this becomes troublesome, speak with your doctor |
Changes to some blood test results | Your doctor will monitor for these |
Less common, but possibly serious side-effects | What should I do if I experience this? |
Pain in your thigh, hip, or groin | Speak with your doctor as soon as possible - these can be signs of a thighbone fracture |
A loose tooth, or jaw pain with swelling or numbness | Speak with your doctor as soon as possible - these can be signs of a problem called osteonecrosis of the jaw |
Ear pain, discharge from an ear, ear infection | These could be signs of a problem called osteonecrosis of the ear. Speak with your doctor straightaway |
यदि आपको कोई अन्य लक्षण महसूस होते हैं जो आपको लगता है कि दवा के कारण हो सकते हैं, तो आगे की सलाह के लिए अपने डॉक्टर या फार्मासिस्ट से बात करें।.
How to store sodium clodronate
सभी दवाओं को बच्चों की पहुँच और दृष्टि से दूर रखें।.
ठंडी, सूखी जगह पर रखें, सीधे गर्मी और रोशनी से दूर।.
सभी दवाओं के बारे में महत्वपूर्ण जानकारी
सभी दवाओं के बारे में महत्वपूर्ण जानकारी
Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
यह दवा आपके लिए है। इसे कभी भी अन्य लोगों को न दें, भले ही उनकी स्थिति आपकी जैसी ही क्यों न लगे।.
पुरानी या अनचाही दवाइयाँ न रखें। उन्हें अपने स्थानीय फार्मेसी में ले जाएँ, जो उन्हें आपके लिए नष्ट कर देगा।.
यदि इस दवा के बारे में आपके कोई प्रश्न हैं तो अपने फार्मासिस्ट से पूछें।.
दवा या टीके के दुष्प्रभावों की रिपोर्ट करें
यदि आपको दुष्प्रभाव महसूस होते हैं, तो आप उन्हें ऑनलाइन रिपोर्ट कर सकते हैं येलो कार्ड वेबसाइट.

दवाओं को मिलाने के बारे में अनिश्चित?
दवाओं, सप्लीमेंट्स और खाद्य पदार्थों के बीच संभावित इंटरैक्शन की जांच करें, उन्हें एक साथ लेने से पहले।.
अक्सर पूछे जाने वाले प्रश्न
How does sodium clodronate specifically help with bone pain in cancer?
Sodium clodronate works by binding to bone and slowing down the process of bone breakdown. This action helps to strengthen bones that may have been weakened by cancer, which in turn reduces the associated bone pain.
Can I take sodium clodronate if I have an existing dental condition like gum disease?
The article mentions that good dental hygiene is important while taking sodium clodronate and that you should tell your dentist you are taking it because some dental treatments may not be recommended. This suggests that pre-existing dental conditions should be discussed with your doctor and dentist.
What specifically should I avoid eating or drinking when taking sodium clodronate?
You should not eat anything for two hours before taking a dose and for one hour after. It is particularly important to avoid milk, including any drinks containing milk, during this entire three-hour period.
Are there any specific supplements or over-the-counter remedies I should be careful about taking with sodium clodronate?
Yes, mineral supplements, iron preparations, and some indigestion remedies should not be taken during the two hours before sodium clodronate and for at least an hour afterwards, as they can reduce the medicine's effectiveness. You should always check with a pharmacist before taking any over-the-counter medicines.
Why do I need regular blood tests while on sodium clodronate treatment?
Regular blood tests are necessary so your doctor can monitor your progress and check for any changes, including potential changes to some blood test results that can be a side-effect of sodium clodronate.
What should I do if I accidentally take more than the prescribed dose of sodium clodronate?
If you suspect you have taken an overdose, you should go to the accident and emergency department of your local hospital immediately. Remember to take the medicine container with you, even if it's empty.
अधिक पठन और संदर्भ
- मेडिसिन्स कम्प्लीट बीएनएफ 89वां संस्करण; ब्रिटिश मेडिकल एसोसिएशन और रॉयल फार्मास्यूटिकल सोसाइटी ऑफ ग्रेट ब्रिटेन, लंदन।.
- Manufacturer's PIL, Loron® 520 mg film-coated tablets; Esteve Pharmaceuticals (formerly Intrapharm Laboratories), The electronic Medicines Compendium. Dated June 2022.
लेखक के बारे मेंपूरा जीवन परिचय देखें

Michael Stewart, MRPharmS
दवा पत्रक समीक्षा प्रबंधक – ठेकेदार, फार्मासिस्ट
BPharm (Hons), MRPharmS
माइकल मिडलैंड्स और साउथ यॉर्कशायर में एक सामुदायिक फार्मासिस्ट हैं, जो दवाओं और चिकित्सा स्थितियों पर सलाह देने में 20 से अधिक वर्षों का अनुभव रखते हैं। उनके पास स्वास्थ्य देखभाल प्रशिक्षण में मजबूत पृष्ठभूमि है, उन्होंने फार्मेसी टीमों और आवासीय देखभाल सेटिंग्स के कर्मचारियों, जिनमें नर्सें शामिल हैं, के लिए प्रशिक्षण पाठ्यक्रम तैयार और प्रस्तुत किए हैं। उन्होंने समुदाय में कम तीव्रता वाली स्थितियों के प्रबंधन के लिए फार्मेसी सलाहकार बोर्डों में भी योगदान दिया है।.
समीक्षक के बारे में

Sid Dajani
सुल्तान दाजानी ने 1994 में लंदन स्कूल ऑफ फार्मेसी से योग्यता प्राप्त की और 1842 में इसकी स्थापना के बाद से रॉयल फार्मास्यूटिकल सोसाइटी परिषद के सबसे युवा निर्वाचित सदस्य बने।.
लेख का इतिहास
इस पृष्ठ पर दी गई जानकारी योग्य चिकित्सकों द्वारा लिखी और सहकर्मी समीक्षा की गई है।.
लेख इन भाषाओं में भी उपलब्ध है अंग्रेज़ी, जर्मन, स्पेनिश, फ्रेंच, इतालवी, पुर्तगाली, हिंदी, हिब्रू, अरबी, और स्वीडिश.
Next review due: 6 Aug 2026
7 Aug 2023 | नवीनतम संस्करण

पूछें, साझा करें, जुड़ें।.
चर्चाओं को ब्राउज़ करें, प्रश्न पूछें, और सैकड़ों स्वास्थ्य विषयों पर अनुभव साझा करें।.
पेशेंट न्यूज़लेटर के लिए साइन अप करें
आपकी साप्ताहिक खुराक स्पष्ट, विश्वसनीय स्वास्थ्य सलाह की - जो आपको सूचित, आत्मविश्वासी और नियंत्रण में महसूस करने में मदद करने के लिए लिखी गई है।.
सदस्यता लेने पर आप हमारी स्वीकार करते हैं गोपनीयता नीति. आप किसी भी समय सदस्यता समाप्त कर सकते हैं। हम कभी भी आपका डेटा नहीं बेचते।.
कैंसर उपचार और दवाओं में अधिक
- बिकलूटामाइड - पुरुषों के लिए एक एंटी-एंड्रोजन
- कैपेसिटाबाइन टैबलेट्स
- क्लोराम्बुसिल टैबलेट्स
- Cyclophosphamide
- साइप्रोटेरोन - पुरुषों के लिए एक एंटी-एंड्रोजन
- प्रोस्टेट कैंसर के लिए एंजालुटामाइड
- गोसरेलीन इम्प्लांट
- हाइड्रोक्सीकार्बामाइड
- हाइड्रोक्सीयूरिया कैप्सूल
- इबैंड्रोनिक एसिड टैबलेट्स और इंजेक्शन
- लापाटिनिब टैबलेट्स
- मेल्फालान टैबलेट्स
- मर्कैप्टोप्यूरिन
- निलोतिनिब कैप्सूल
- फेनोक्सीबेंजामाइन - एक अल्फा-ब्लॉकर
- पोनाटिनिब टैबलेट्स
- सोरेफेनिब टैबलेट्स
- स्तन कैंसर के लिए टोरेमिफीन
- ट्रियोसल्फन
- ट्रेटिनॉइन कैप्सूल